The Drawings and Prints Cabinet is located on the top floor of Palazzo Rosso and is part of the Strada Nuova Museums complex.

The collections are located in chests of drawers specially designed by Franco Albini in 1961 and are cyclically exhibited in monographic exhibitions. 

The drawing collection is made of 10,000 sheets and is recognized as one of the most important on the national scene: of particular importance are the sheets from the Genoese school (from the sixteenth to the nineteenth century), Emilian (with masterpieces by Guercino and Guido Reni) and Roman (numerous sheets by the great portraitist of Caravaggio's Rome, Ottavio Leoni). Among the most important drawings is the famous self-portrait by Giuseppe Arcimboldo (1584).

The print collection has around 7,000 engravings, with prestigious examples from the Italian, German and Flemish areas.